Transmission by blood transfusion. It is found mainly in 21 Latin American countries1, where it is mostly vector-borne. B, Number of cases of acute Chagas disease in Brazil according to type of transmission, 2000–2010. Oral transmission of Trypanosoma cruzi, the causative agent of Chagas disease, is the most important route of infection in Brazilian Amazon and Venezuela.Other South American countries have also reported outbreaks associated with food consumption.

Chronic gastrointestinal problems (such as megaesophagus or megacolon) are less common and may develop with or without cardiac manifestations. Mass migration of chronically infected and asymptomatic persons has caused globalization of Chagas disease and has made nonvectorial infection, including vertical and blood-borne transmission, more of a threat to human communities than vectorial infection. By some estimates every hour a baby is born with Chagas Disease. Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis. Chagas disease is a chronic infection that kills approximately 12,000 people a year. A parasite called Trypanosoma cruzi (T. cruzi) causes it. Although these parasites are rarely transmitted by insects in the United States, there is concern that vector transmission may increase ().Chagas disease, endemic to most of Latin America, can be transmitted to mammals by >130 species of blood-feeding insect vectors (subfamily Triatominae). Chagas disease is an infection caused by a protozoan parasite (Trypanosoma cruzi) that can result in acute inflammatory skin changes (chagomas). Read more about symptoms, transmission from kissing bugs, diagnosis, treatment, prevention, history, and research. A recent study showed the importance of parasite contact with oral cavity to induce a highly severe acute disease in mice. Chagas disease is a vector-borne disease caused by Trypanosoma cruzi trypanosomes. Chagas disease is an infection caused by a protozoan parasite (Trypanosoma cruzi) that can result in acute inflammatory skin changes (chagomas). Up until recently control and prevention strategies for Chagas disease largely relied on the early detection and treatment of infected newborns and siblings of pregnant women.
Our goal is to halt transmission of vector-borne disease.
It is estimated that as many as 8 million people in Mexico, Central America, and South America have Chagas disease, most of whom do not know they are infected. A, Acute Chagas disease in Brazil, by municipality, 2000–2010. Chronic Chagas disease usually affects the heart; clinical signs include conduction system abnormalities, ventricular arrhythmias, and in late-stage disease, congestive cardiomyopathy.

This insect normally hides during the day and becomes active at night, when it feeds on human blood.

In the Chagas disease–endemic regions of South and Central America, the primary risk for insect transmission to humans is related to the efficiency with which local vector species can invade and colonize homes, resulting in a domestic transmission cycle for what is otherwise exclusively a zoonotic disease in the southern United States. Chagas disease is now an active disease in the urban centers of countries of nonendemicity and endemicity because of congenital and blood and/or organ transplantation transmissions and the reactivation of the chronic disease in smaller scale than vectorial transmission, reported as controlled in countries of endemicity.

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